Coordinating Center for Technical Assistance

Working together to improve health outcomes for people living with HIV.

A red HIV Awareness ribbon.

The E2i Project

Using Evidence-Informed Interventions (E2i) to Improve Health Outcomes among People Living with HIV

There is great need for implementation of evidence-informed interventions to reduce HIV-related health disparities and improve health outcomes among people living with HIV (PLWH). While research is defining best practices for addressing steps along the HIV care continuum, the implementation and dissemination of such interventions lags behind.

The Health Resources and Services Administration HIV/AIDS Bureau’s Evidence-informed Interventions initiative (E2i) supports 26 Ryan White HIV/AIDS Program recipients in the implementation and evaluation of evidence-informed interventions in four focus areas:

  • Improving HIV health outcomes for transgender women
  • Improving HIV health outcomes for Black MSM
  • Integrating behavioral health with primary medical care for people living with HIV/AIDS
  • Identifying and addressing trauma among people living with HIV/AIDS

Who We Are

The Fenway Institute, in partnership with AIDS United, serves as the E2i Coordinating Center for Technical Assistance (CCTA).
The University of California San Francisco Center for AIDS Prevention Studies serves as the E2i Evaluation Center (EC).


This project is supported by the Health Resources and Services Administration’s (HRSA) HIV/AIDS Bureau (HAB) of the U.S. Department of Health and Human Services (HHS) under grant number U69HA31067. National Training and Technical Assistance is funded for $5,324,429.00 and 0% financed with nongovernmental sources. This information or content and conclusions are those of the author and should not be construed as the official position or policy of, nor should any endorsements be inferred by HRSA, HHS or the U.S. Government.